Fibrocyte-like cells mediate acquired resistance to anti-angiogenic therapy with bevacizumab

Bevacizumab exerts anti-angiogenic effects in cancer patients by inhibiting vascular endothelial growth factor (VEGF). However, its use is still limited due to the development of resistance to the treatment. Such resistance can be regulated by various factors, although the underlying mechanisms rema...

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Vydáno v:Nat Commun
Hlavní autoři: Mitsuhashi, Atsushi, Goto, Hisatsugu, Saijo, Atsuro, Trung, Van The, Aono, Yoshinori, Ogino, Hirokazu, Kuramoto, Takuya, Tabata, Sho, Uehara, Hisanori, Izumi, Keisuke, Yoshida, Mitsuteru, Kobayashi, Hiroaki, Takahashi, Hidefusa, Gotoh, Masashi, Kakiuchi, Soji, Hanibuchi, Masaki, Yano, Seiji, Yokomise, Hiroyasu, Sakiyama, Shoji, Nishioka, Yasuhiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686833/
https://ncbi.nlm.nih.gov/pubmed/26635184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9792
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