Conserved C-terminal Charge Exerts a Profound Influence on the Aggregation Rate of α-Synuclein

α-synuclein is the major component of filamentous Lewy bodies found in the brains of patients diagnosed with Parkinson’s disease. Recent studies demonstrate that, in addition to the wild-type sequence, α-synuclein is found in several modified forms, including truncated and phosphorylated species. Al...

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Detalhes bibliográficos
Main Authors: Levitan, Katerina, Chereau, David, Cohen, Samuel I. A., Knowles, Tuomas P. J., Dobson, Christopher M., Fink, Anthony L., Anderson, John P., Goldstein, Jason M., Millhauser, Glenn L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143250/
https://ncbi.nlm.nih.gov/pubmed/21689664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.05.046
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