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Extensive Aspartoacylase Expression in the Rat Central Nervous System
Aspartoacylase (ASPA) catalyzes deacetylation of N-acetylaspartate (NAA) to generate acetate and aspartate. Mutations in the gene for ASPA lead to reduced acetate availability in the CNS during development resulting in the fatal leukodystrophy Canavan disease. Highly specific polyclonal antibodies t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3143213/ https://ncbi.nlm.nih.gov/pubmed/21598311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21186 |
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