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Cytotoxic mAb from rheumatic carditis recognizes heart valves and laminin

Anti-streptococcal antibodies cross-reactive with N-acetyl-βD-glucosamine (GlcNAc) and myosin are present in the sera of patients with rheumatic fever (RF). However, their role in tissue injury is not clear. In this study, we show that anti-GlcNAc/anti-myosin mAb 3.B6 from a rheumatic carditis patie...

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Detalhes bibliográficos
Main Authors: Galvin, Jeffrey E., Hemric, Mark E., Ward, Kent, Cunningham, Madeleine W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC314302/
https://ncbi.nlm.nih.gov/pubmed/10903337
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