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Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination

Fast axonal conduction depends on myelin, which is formed by Schwann cells in the PNS. We found that the transcription factor Yin Yang 1 (YY1) is crucial for peripheral myelination. Conditional ablation of Yy1 in the Schwann cell lineage resulted in severe hypomyelination, which occurred independent...

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Bibliografski detalji
Glavni autori: He, Ye, Kim, Jin Young, Dupree, Jeffrey, Tewari, Ambika, Melendez-Vasquez, Carmen, Svaren, John, Casaccia, Patrizia
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142946/
https://ncbi.nlm.nih.gov/pubmed/21057508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2686
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