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Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination

Fast axonal conduction depends on myelin, which is formed by Schwann cells in the PNS. We found that the transcription factor Yin Yang 1 (YY1) is crucial for peripheral myelination. Conditional ablation of Yy1 in the Schwann cell lineage resulted in severe hypomyelination, which occurred independent...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: He, Ye, Kim, Jin Young, Dupree, Jeffrey, Tewari, Ambika, Melendez-Vasquez, Carmen, Svaren, John, Casaccia, Patrizia
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142946/
https://ncbi.nlm.nih.gov/pubmed/21057508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2686
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