The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1

The Vpr protein of HIV-1 functions as a vital accessory gene by regulating various cellular functions, including cell differentiation, apoptosis, nuclear factor of κB (NF-κB) suppression and cell-cycle arrest of the host cell. Several reports have indicated that Vpr complexes with the glucocorticoid...

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Hlavní autoři: Muthumani, Karuppiah, Choo, Andrew Y., Zong, Wei-Xing, Madesh, Muniswamy, Hwang, Daniel S., Premkumar, Arumugam, Thieu, Khanh P., Emmanuel, Joann, Kumar, Sanjeev, Thompson, Craig B., Weiner, David B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142937/
https://ncbi.nlm.nih.gov/pubmed/16429131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1352
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