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Antisense-Mediated RNA Targeting: Versatile and Expedient Genetic Manipulation in the Brain

A limiting factor in brain research still is the difficulty to evaluate in vivo the role of the increasing number of proteins implicated in neuronal processes. We discuss here the potential of antisense-mediated RNA targeting approaches. We mainly focus on those that manipulate splicing (exon skippi...

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Bibliographic Details
Main Authors: Zalachoras, Ioannis, Evers, Melvin M., van Roon-Mom, Willeke M. C., Aartsma-Rus, Annemieke M., Meijer, Onno C.
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142880/
https://ncbi.nlm.nih.gov/pubmed/21811437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2011.00010
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