Identification of Antibiotic Stress-Inducible Promoters: A Systematic Approach to Novel Pathway-Specific Reporter Assays for Antibacterial Drug Discovery

As present antibiotics therapy becomes increasingly ineffectual, new technologies are required to identify and develop novel classes of antibacterial agents. An attractive alternative to the classical target-based approach is the use of promoter-inducible reporter assays for high-throughput screenin...

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Hlavní autoři: Fischer, Hans Peter, Brunner, Nina A., Wieland, Bernd, Paquette, Jesse, Macko, Ludwig, Ziegelbauer, Karl, Freiberg, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2004
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Letters
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC314284/
https://ncbi.nlm.nih.gov/pubmed/14707172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1275704
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