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Challenges of Antibacterial Discovery

Summary: The discovery of novel small-molecule antibacterial drugs has been stalled for many years. The purpose of this review is to underscore and illustrate those scientific problems unique to the discovery and optimization of novel antibacterial agents that have adversely affected the output of t...

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Detalhes bibliográficos
Autor principal: Silver, Lynn L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021209/
https://ncbi.nlm.nih.gov/pubmed/21233508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CMR.00030-10
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