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Lack of evidence of CD40 ligand involvement in transfusion-related acute lung injury

Activated platelets have been implicated in playing a major role in transfusion-related acute lung injury (TRALI), as platelets can trigger neutrophils, resulting in vascular damage. We hypothesized that binding of platelet CD40 ligand (CD40L) to endothelial CD40 is essential in the onset of TRALI....

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Autori principali: Tuinman, P R, Gerards, M C, Jongsma, G, Vlaar, A P, Boon, L, Juffermans, N P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142652/
https://ncbi.nlm.nih.gov/pubmed/21605114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2011.04422.x
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