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Ethanol as a Prodrug: Brain Metabolism of Ethanol Mediates its Reinforcing effects

BACKROUND: While the molecular entity responsible for the rewarding effects of virtually all drugs of abuse is known; that for ethanol remains uncertain. Some lines of evidence suggest that the rewarding effects of alcohol are mediated not by ethanol per se but by acetaldehyde generated by catalase...

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Detalhes bibliográficos
Main Authors: Karahanian, Eduardo, Quintanilla, María Elena, Tampier, Lutske, Rivera-Meza, Mario, Bustamante, Diego, Gonzalez-Lira, Víctor, Morales, Paola, Herrera-Marschitz, Mario, Israel, Yedy
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142559/
https://ncbi.nlm.nih.gov/pubmed/21332529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2011.01439.x
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