Bioluminescence resonance energy transfer (BRET) imaging of protein–protein interactions within deep tissues of living subjects

Identifying protein–protein interactions (PPIs) is essential for understanding various disease mechanisms and developing new therapeutic approaches. Current methods for assaying cellular intermolecular interactions are mainly used for cells in culture and have limited use for the noninvasive assessm...

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Bibliografiska uppgifter
Huvudupphovsmän: Dragulescu-Andrasi, Anca, Chan, Carmel T., De, Abhijit, Massoud, Tarik F., Gambhir, Sanjiv S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141927/
https://ncbi.nlm.nih.gov/pubmed/21730157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100923108
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