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Effects of Repeated Treatment with Phosphodiesterase-4 Inhibitors on cAMP Signaling, Hippocampal Cell Proliferation, and Behavior in the Forced-Swim Test

The effects of repeated treatment with the phosphodiesterase-4 (PDE4) inhibitors rolipram, piclamilast, and 4-(2-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-phenylethyl)pyridine (CDP840), which differ in their interactions with high- and low-affinity binding conformers of the enzyme, were contrasted to t...

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Bibliografiset tiedot
Päätekijät: Xiao, Lan, O'Callaghan, James P., O'Donnell, James M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Pharmacology and Experimental Therapeutics 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141907/
https://ncbi.nlm.nih.gov/pubmed/21566211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.179358
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