Activation and Regulation of Purinergic P2X Receptor Channels

Mammalian ATP-gated nonselective cation channels (P2XRs) can be composed of seven possible subunits, denoted P2X1 to P2X7. Each subunit contains a large ectodomain, two transmembrane domains, and intracellular N and C termini. Functional P2XRs are organized as homomeric and heteromeric trimers. This...

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Bibliographic Details
Main Authors: Coddou, Claudio, Yan, Zonghe, Obsil, Tomas, Huidobro-Toro, J. Pablo, Stojilkovic, Stanko S.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2011
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Review Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141880/
https://ncbi.nlm.nih.gov/pubmed/21737531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.110.003129
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