Opposing Roles of Calcium and Intracellular ATP on Gating of the Purinergic P2X2 Receptor Channel

P2X2 receptors (P2X2R) exhibit a slow desensitization during the initial ATP application and a progressive, calcium-dependent increase in rates of desensitization during repetitive stimulation. This pattern is observed in whole-cell recordings from cells expressing recombinant and native P2X2R. Howe...

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Опубликовано в: :Int J Mol Sci
Главные авторы: Rokic, Milos B., Castro, Patricio, Leiva-Salcedo, Elias, Tomic, Melanija, Stojilkovic, Stanko S., Coddou, Claudio
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979340/
https://ncbi.nlm.nih.gov/pubmed/29641486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041161
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