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Gβγ subunits inhibit Epac-induced melanoma cell migration
BACKGROUND: Recently we reported that activation of Epac1, an exchange protein activated by cAMP, increases melanoma cell migration via Ca (2+ )release from the endoplasmic reticulum (ER). G-protein βγ subunits (Gβγ) are known to act as an independent signaling molecule upon activation of G-protein...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3141774/ https://ncbi.nlm.nih.gov/pubmed/21679469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-256 |
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