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FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells

BACKGROUND: Alterations towards a permissive stromal microenvironment provide important cues for tumor growth, invasion, and metastasis. In this study, Fibroblast activation protein (FAP), a serine protease selectively produced by tumor-associated fibroblasts in over 90% of epithelial tumors, was us...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lee, Hyung-Ok, Mullins, Stefanie R, Franco-Barraza, Janusz, Valianou, Matthildi, Cukierman, Edna, Cheng, Jonathan D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141768/
https://ncbi.nlm.nih.gov/pubmed/21668992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-245
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