A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria

Parasitized red blood cells (RBCs) from children suffering from severe malaria often adhere to complement receptor 1 (CR1) on uninfected RBCs to form clumps of cells known as “rosettes.” Despite a well documented association between rosetting and severe malaria, it is controversial whether rosetting...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Cockburn, Ian A., Mackinnon, Margaret J., O'Donnell, Angela, Allen, Stephen J., Moulds, Joann M., Baisor, Moses, Bockarie, Moses, Reeder, John C., Rowe, J. Alexandra
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314175/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14694201/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0305306101
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