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Hybridoma-free generation of monoclonal antibodies
Production of monoclonal antibodies requires immortalization of splenocytes by somatic fusion to a myeloma cell line partner (hybridomas). Although hybridomas can be immortal, they may depend on a feeder cell layer and may be genetically unstable. Since the inception of hybridoma technology, efforts...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314172/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14688405/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0305834101 |
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