An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin

BACKGROUND: In vitro cell systems together with omics methods represent promising alternatives to conventional animal models for toxicity testing. Transcriptomic and proteomic approaches have been widely applied in vitro but relatively few studies have used metabolomics. Therefore, the goal of the p...

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Detaylı Bibliyografya
Asıl Yazarlar: Ruiz-Aracama, Ainhoa, Peijnenburg, Ad, Kleinjans, Jos, Jennen, Danyel, van Delft, Joost, Hellfrisch, Caroline, Lommen, Arjen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141663/
https://ncbi.nlm.nih.gov/pubmed/21599895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-251
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