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Blocking premature reverse transcription fails to rescue the HIV-1 nucleocapsid-mutant replication defect
BACKGROUND: The nucleocapsid (NC) protein of HIV-1 is critical for viral replication. Mutational analyses have demonstrated its involvement in viral assembly, genome packaging, budding, maturation, reverse transcription, and integration. We previously reported that two conservative NC mutations, His...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
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BioMed Central
2011
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3141651/ https://ncbi.nlm.nih.gov/pubmed/21682883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-46 |
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