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Mutations in Human Immunodeficiency Virus Type 1 Nucleocapsid Protein Zinc Fingers Cause Premature Reverse Transcription

Human immunodeficiency virus type 1 (HIV-1) requires that its genome be reverse transcribed into double-stranded DNA for productive infection of cells. This process requires not only reverse transcriptase but also the nucleocapsid protein (NC), which functions as a nucleic acid chaperone. Reverse tr...

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Detalhes bibliográficos
Main Authors: Thomas, James A., Bosche, William J., Shatzer, Teresa L., Johnson, Donald G., Gorelick, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546943/
https://ncbi.nlm.nih.gov/pubmed/18667500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00583-08
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