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An essential role for trimethylguanosine RNA caps in Saccharomyces cerevisiae meiosis and their requirement for splicing of SAE3 and PCH2 meiotic pre-mRNAs

Tgs1 is the enzyme that converts m(7)G RNA caps to the 2,2,7-trimethylguanosine (TMG) caps characteristic of spliceosomal snRNAs. Fungi grow vegetatively without TMG caps, thereby raising the question of what cellular transactions, if any, are TMG cap-dependent. Here, we report that Saccharomyces ce...

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Detalles Bibliográficos
Autores principales: Qiu, Zhicheng R., Shuman, Stewart, Schwer, Beate
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141232/
https://ncbi.nlm.nih.gov/pubmed/21398639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr083
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