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Continual Reassessment Method for Partial Ordering
Much of the statistical methodology underlying the experimental design of Phase 1 trials in oncology is intended for studies involving a single cytotoxic agent. The goal of these studies is to estimate the maximally tolerated dose, the highest dose that can be administered with an acceptable level o...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3141101/ https://ncbi.nlm.nih.gov/pubmed/21361888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2011.01560.x |
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