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Continual Reassessment Method for Partial Ordering

Much of the statistical methodology underlying the experimental design of Phase 1 trials in oncology is intended for studies involving a single cytotoxic agent. The goal of these studies is to estimate the maximally tolerated dose, the highest dose that can be administered with an acceptable level o...

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Hlavní autoři: Wages, Nolan A., Conaway, Mark R., O’Quigley, John
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141101/
https://ncbi.nlm.nih.gov/pubmed/21361888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2011.01560.x
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