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Vascular Calcification and Aortic Fibrosis: A Bifunctional Role for Osteopontin In Diabetic Arteriosclerosis
OBJECTIVE: Calcification and fibrosis reduce vascular compliance in arteriosclerosis. To better understand the role of osteopontin (OPN), a multifunctional protein upregulated in diabetic arteries, we evaluated contributions of OPN in male LDLR−/− mice fed high fat diets (HFD). METHODS AND RESULTS:...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3141097/ https://ncbi.nlm.nih.gov/pubmed/21597007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.230011 |
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