A Role for the Chemokine RANTES in Regulating CD8 T Cell Responses during Chronic Viral Infection

RANTES (CCL5) is a chemokine expressed by many hematopoietic and non-hematopoietic cell types that plays an important role in homing and migration of effector and memory T cells during acute infections. The RANTES receptor, CCR5, is a major target of anti-HIV drugs based on blocking viral entry. How...

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Bibliographic Details
Main Authors: Crawford, Alison, Angelosanto, Jill Marie, Nadwodny, Kim Lynn, Blackburn, Shawn D., Wherry, E. John
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141034/
https://ncbi.nlm.nih.gov/pubmed/21814510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002098
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