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Regulation of the 26S Proteasome Complex During Oxidative Stress

The proteasome plays a pivotal role in the cellular response to oxidative stress. Here, we used biochemical and mass spectrometric methods to investigate structural changes in the 26S proteasomes from yeast and mammalian cells exposed to hydrogen peroxide (H(2)O(2)). Oxidative stress induced the dis...

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Autori principali: Wang, Xiaorong, Yen, James, Kaiser, Peter, Huang, Lan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140957/
https://ncbi.nlm.nih.gov/pubmed/21139140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2001232
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