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The Parkinsonian Mimetic, MPP(+), Specifically Impairs Mitochondrial Transport in Dopamine Axons

Impaired axonal transport may play a key role in Parkinson's disease. To test this notion, a microchamber system was adapted to segregate axons from cell bodies using green fluorescent protein-labeled mouse dopamine (DA) neurons. Transport was examined in axons challenged with the DA neurotoxin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim-Han, Jeong Sook, Antenor-Dorsey, Jo Ann, O'Malley, Karen L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140916/
https://ncbi.nlm.nih.gov/pubmed/21562285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0711-11.2011
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