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Tolerance and cross-tolerance to cannabinoids in mice: schedule-controlled responding and hypothermia

RATIONALE: Cannabinoid CB(1) receptor agonists vary in efficacy in vitro; however, relationships between efficacy and behavioral effects are unclear. OBJECTIVE: This study examined the relationship between apparent CB(1) agonist efficacy and in vivo effects. METHODS: Male C57BL/6J mice responded for...

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Detalhes bibliográficos
Main Authors: Singh, Harinder, Schulze, David R., McMahon, Lance R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140914/
https://ncbi.nlm.nih.gov/pubmed/21246187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-2162-7
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