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Extracellular release of ATP mediated by cyclic mechanical stress leads to mobilization of Arachidonic Acid in Trabecular Meshwork cells

PURPOSE: To investigate the mechanisms that mediate the release of ATP induced by cyclic mechanical stress (CMS) and the role of extracellular ATP in the mobilization of arachidonic acid (AA) and prostaglandin secretion. METHODS: Porcine TM cells (pTM) were subjected to CMS. Extracellular ATP was de...

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Detalhes bibliográficos
Main Authors: Luna, Coralia, Li, Guorong, Qiu, Jianming, Challa, Pratap, Epstein, David L., Gonzalez, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140847/
https://ncbi.nlm.nih.gov/pubmed/19608543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-3796
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