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MicroRNA-24 Regulates the Processing of Latent TGFβ1 During Cyclic Mechanical Stress in Human Trabecular Meshwork Cells Through Direct Targeting of FURIN
Cyclic mechanical stress (CMS) leads(Q1) to alterations of cellular functions in the trabecular meshwork (TM), including the up-regulation of transforming growth factor beta 1 (TGFβ1), that can potentially contribute to the pathogenesis of glaucoma. Although microRNAs (miRNAs) are known to play impo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3152464/ https://ncbi.nlm.nih.gov/pubmed/20945401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22476 |
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