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Functional analysis of the RNF114 psoriasis susceptibility gene implicates innate immune responses to double-stranded RNA in disease pathogenesis

Psoriasis is an immune-mediated skin disease, the aetiology of which remains poorly understood. In recent years, genome-wide association studies (GWAS) have helped to illuminate the molecular basis of this condition, by demonstrating the pathogenic involvement of multiple genes from the IL-23 and NF...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Bijlmakers, Marie-José, Kanneganti, Seshu K., Barker, Jonathan N., Trembath, Richard C., Capon, Francesca
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140818/
https://ncbi.nlm.nih.gov/pubmed/21571784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr215
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