The ARF tumor suppressor inhibits tumor cell colonization independent of p53 in a novel mouse model of pancreatic ductal adenocarcinoma metastasis

Pancreatic ductal adenocarcinoma (PDAC) is an incurable, highly metastatic disease that is largely resistant to existing treatments. A better understanding of the genetic basis of PDAC metastasis should facilitate development of improved therapies. To that end, we developed a novel mouse xenograft m...

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Detalhes bibliográficos
Main Authors: Muniz, Viviane Palhares, Barnes, J. Matthew, Paliwal, Seema, Zhang, Xuefeng, Tang, Xiaoyun, Chen, Songhai, Zamba, Kokou D., Cullen, Joseph J., Meyerholz, David K., Meyers, Shari, Davis, J. Nathan, Grossman, Steven R., Henry, Michael D., Quelle, Dawn E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140613/
https://ncbi.nlm.nih.gov/pubmed/21636682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0475
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