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Strong Association of 677 C>T Substitution in the MTHFR Gene with Male Infertility - A Study on an Indian Population and a Meta-Analysis

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is an important enzyme of folate and methionine metabolism, making it crucial for DNA synthesis and methylation. The objective of this study was to analyze MTHFR gene 677C>T polymorphism in infertile male individuals from North India, follow...

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Detalhes bibliográficos
Main Authors: Gupta, Nishi, Gupta, Saraswati, Dama, Madhukar, David, Archana, Khanna, Geeta, Khanna, Anil, Rajender, Singh
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140509/
https://ncbi.nlm.nih.gov/pubmed/21799811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022277
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