Genetic Cross-Interaction between APOE and PRNP in Sporadic Alzheimer's and Creutzfeldt-Jakob Diseases

Alzheimer's disease (AD) and Creutzfeldt-Jakob disease (CJD) represent two distinct clinical entities belonging to a wider group, generically named as conformational disorders that share common pathophysiologic mechanisms. It is well-established that the APOE ε4 allele and homozygosity at polym...

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Autori principali: Calero, Olga, Bullido, María J., Clarimón, Jordi, Frank-García, Ana, Martínez-Martín, Pablo, Lleó, Alberto, Rey, María Jesús, Rábano, Alberto, Blesa, Rafael, Gómez-Isla, Teresa, Valdivieso, Fernando, de Pedro-Cuesta, Jesús, Ferrer, Isidro, Calero, Miguel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140492/
https://ncbi.nlm.nih.gov/pubmed/21799773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022090
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