A Common BACE1 Polymorphism Is a Risk Factor for Sporadic Creutzfeldt-Jakob Disease

The β site APP cleaving enzyme 1 (BACE1) is the rate-limiting β-secretase enzyme in the amyloidogenic processing of APP and Aβ formation, and therefore it has a prominent role in Alzheimer’s disease (AD) pathology. Recent evidence suggests that the prion protein (PrP) interacts directly with BACE1 r...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Calero, Olga, Bullido, María J., Clarimón, Jordi, Frank-García, Ana, Martínez-Martín, Pablo, Lleó, Alberto, Rey, María Jesús, Sastre, Isabel, Rábano, Alberto, de Pedro-Cuesta, Jesús, Ferrer, Isidro, Calero, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431402/
https://ncbi.nlm.nih.gov/pubmed/22952813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043926
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados