Comparison of Liquid Chromatography–Tandem Mass Spectrometry and Sandwich ELISA for Determination of Keratan Sulfate in Plasma and Urine

BACKGROUND AND AIM: Mucopolysaccharidosis IVA (MPS IVA) leads to skeletal dysplasia through excessive storage of chondroitin-6-sulfate and keratan sulfate (KS). KS is synthesized mainly in cartilage and released into circulation, making it a critical biomarker for MPS IVA to evaluate clinical course...

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Autori principali: Hintze, Jonathan P., Tomatsu, Shunji, Fujii, Tadashi, Montaño, Adriana M., Yamaguchi, Seiji, Suzuki, Yasuyuki, Fukushi, Masaru, Ishimaru, Takeshi, Orii, Tadao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Libertas Academica 2011
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140273/
https://ncbi.nlm.nih.gov/pubmed/21792275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BMI.S7451
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