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MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly

When T cells are activated, the expression of the CD95 ligand is elevated, with the purpose of inducing apoptosis in target cells and to later eliminate the activated T cells. We have shown previously that mitogen-activated protein kinase (MAPK or ERK) signaling suppresses CD95-mediated apoptosis in...

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Xehetasun bibliografikoak
Egile Nagusiak: Holmström, Tim H., Schmitz, Ingo, Söderström, Thomas S., Poukkula, Minna, Johnson, Victoria L., Chow, Sek C., Krammer, Peter H., Eriksson, John E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC314013/
https://ncbi.nlm.nih.gov/pubmed/11032809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.20.5418
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