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Targeting of the pro-apoptotic VDAC-like porin (PorB) of Neisseria gonorrhoeae to mitochondria of infected cells

Infection of cell cultures with Neisseria gonorrhoeae results in apoptosis that is mediated by the PorB porin. During the infection process porin translocates from the outer bacterial membrane into host cell membranes where its channel activity is regulated by nucleotide binding and voltage-dependen...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Müller, Anne, Günther, Dirk, Brinkmann, Volker, Hurwitz, Robert, Meyer, Thomas F., Rudel, Thomas
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314008/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11032801/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.20.5332
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