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Targeting of the pro-apoptotic VDAC-like porin (PorB) of Neisseria gonorrhoeae to mitochondria of infected cells

Infection of cell cultures with Neisseria gonorrhoeae results in apoptosis that is mediated by the PorB porin. During the infection process porin translocates from the outer bacterial membrane into host cell membranes where its channel activity is regulated by nucleotide binding and voltage-dependen...

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Autori principali: Müller, Anne, Günther, Dirk, Brinkmann, Volker, Hurwitz, Robert, Meyer, Thomas F., Rudel, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC314008/
https://ncbi.nlm.nih.gov/pubmed/11032801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.20.5332
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