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A Cautionary Note on the Evaluation of Biomarkers of Subtypes of a Single Disease

Heterogeneity in the molecular characteristics of a disease presents a challenge to investigators attempting to identify biomarkers of the disease. Preceding the biomarker discovery effort with stratification within a heterogeneous disease group, which amounts to grouping disease cases into more hom...

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Main Authors: Adewale, Adeniyi J., Liu, Qi, Dinu, Irina, Lampe, Paul D., Mitchell, Bree L., Yasui, Yutaka
格式: Artigo
語言:Inglês
出版: Oxford University Press 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139966/
https://ncbi.nlm.nih.gov/pubmed/18632592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwn183
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