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A Cautionary Note on the Evaluation of Biomarkers of Subtypes of a Single Disease
Heterogeneity in the molecular characteristics of a disease presents a challenge to investigators attempting to identify biomarkers of the disease. Preceding the biomarker discovery effort with stratification within a heterogeneous disease group, which amounts to grouping disease cases into more hom...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3139966/ https://ncbi.nlm.nih.gov/pubmed/18632592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwn183 |
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