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Two modes of FEN1 binding to PCNA regulated by DNA

The FEN1 nuclease functions during Okazaki fragment maturation in the eukaryotic cell. Like many other proliferating cell nuclear antigen (PCNA)-binding proteins, FEN1 interacts with the interdomain connector loop (IDCL) of PCNA, and PCNA greatly stimulates FEN1 activity. A yeast IDCL mutant pcna-79...

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書目詳細資料
發表在:EMBO J
Principais autores: Gomes, Xavier V., Burgers, Peter M.J.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2000
主題:
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313985/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10899134/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.14.3811
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