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Two modes of FEN1 binding to PCNA regulated by DNA
The FEN1 nuclease functions during Okazaki fragment maturation in the eukaryotic cell. Like many other proliferating cell nuclear antigen (PCNA)-binding proteins, FEN1 interacts with the interdomain connector loop (IDCL) of PCNA, and PCNA greatly stimulates FEN1 activity. A yeast IDCL mutant pcna-79...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC313985/ https://ncbi.nlm.nih.gov/pubmed/10899134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.14.3811 |
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