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Phasic characteristic of elementary Ca(2+) release sites underlies quantal responses to IP(3)
Ca(2+) liberation by inositol 1,4,5-trisphosphate (IP(3)) is ‘quantal’, in that low [IP(3)] causes only partial Ca(2+) release, but further increasing [IP(3)] evokes more release. This characteristic allows cells to generate graded Ca(2+) signals, but is unexpected, given the regenerative nature of...
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| Published in: | EMBO J |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2000
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313983/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10899115/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.14.3608 |
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