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Imaging the quantal substructure of single IP(3)R channel activity during Ca(2+) puffs in intact mammalian cells

The spatiotemporal patterning of Ca(2+) signals regulates numerous cellular functions, and is determined by the functional properties and spatial clustering of inositol trisphosphate receptor (IP(3)R) Ca(2+) release channels in the endoplasmic reticulum membrane. However, studies at the single-chann...

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Autori principali: Smith, Ian F., Parker, Ian
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669345/
https://ncbi.nlm.nih.gov/pubmed/19332787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810799106
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