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SsrA-mediated tagging and proteolysis of LacI and its role in the regulation of lac operon

SsrA RNA of Escherichia coli, also known as 10Sa RNA or tmRNA, acts both as tRNA and mRNA when ribosomes are paused at the 3′ end of an mRNA lacking a stop codon. This process, referred to as trans-translation, leads to the addition of a short peptide tag to the C-terminus of the incomplete nascent...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Abo, Tatsuhiko, Inada, Toshifumi, Ogawa, Kazuko, Aiba, Hiroji
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313975/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10899129/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.14.3762
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