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SsrA-mediated tagging and proteolysis of LacI and its role in the regulation of lac operon

SsrA RNA of Escherichia coli, also known as 10Sa RNA or tmRNA, acts both as tRNA and mRNA when ribosomes are paused at the 3′ end of an mRNA lacking a stop codon. This process, referred to as trans-translation, leads to the addition of a short peptide tag to the C-terminus of the incomplete nascent...

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Autors principals: Abo, Tatsuhiko, Inada, Toshifumi, Ogawa, Kazuko, Aiba, Hiroji
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC313975/
https://ncbi.nlm.nih.gov/pubmed/10899129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.14.3762
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